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kaninerna - Swedish-English Dictionary - Glosbe

Owing to its narrow therapeutic index, numerous intoxication have been reported in target/non-target animals by overdosage, misuse or drug interactions as well as human who consumed salinomycin accidently. Salinomycin is currently approved by the FDA in the United States and is used around the world. It is used as a supplement in poultry feed, and in particular for broiler chickens. It is a bestselling feed additive for chickens and contributes to producing millions of tons of disease free chicken meat throughout the world. Salinomycin is widely used as a feed additive to control coccidiosis in the broiler industry world-wide. EC legislation on veterinary drug residues will soon be extended to cover poultry.

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The readers direction are being accepted. This paper summarizes the current state of knowledge on the toxicity of salinomycin and narasin in turkeys. It reviews the data concerning the symptoms, mortality rate and possible causes of USE: Salinomycin is used as an antibiotic in poultry, cattle and sheep. EXPOSURE: Workers that use salinomycin may breathe in dust or have direct skin contact.

Nyhetsbrev från SVA:s enhet för kemi, miljö och - VFK

Nöt. Cattle. Häst. Horse. Hund/Katt.

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Salinomycin poultry

These polyether acid ionophore antimicrobials are produced by the Actinomycetales order of filamentous bacteria. These drugs are widely used to control or prevent coccidian parasite infestation in the intestinal tracts of poultry, cattle, and pigs. Comparison of the effect of probiotic, prebiotic, salinomycin and vaccine in control of coccidiosis in broiler chickens.

Salinomycin poultry

Broiler, roaster and replacement (breeder and layer) chickens Use Sacox 60 to provide salinomycin sodium concentrations ranging from 40-60 g/ton (0.0044% to 0.0066%) for the prevention of coccidiosis in broiler, roaster and replacement chickens caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti and E. mivati. Toxicities occur when broiler feed containing salinomycin is accidentally fed to naive breeder hens. Clinical signs in these hen flocks include paralysis with the legs extended backward and decreased feed consumption, egg production, and hatchability. Levels of salinomycin >10 g/ton in breeder-hen feed are sufficient to produce these clinical signs. Salinomycin is widely used as a feed additive to control coccidiosis in the broiler industry world‐wide. EC legislation on veterinary drug residues will soon be extended to cover poultry. This will require the development of rapid assays to screen for the presence of residual concentrations of this and other drugs in poultry meat.
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Description: Narasin belongs to the polyether monocarboxylic acid class of ionophores. Origin: Fermentation product of Streptomyces aureofaciens.. Mode of Action: The biological activity of narasin is based on its ability to form lipid soluble and dynamically reversible complexes with cations, preferably monovalent cations such as alkaline K+, Na+ and Rb+: Narasin functions as a carrier of Journal: Poultry science 20120901 Title: Salinomycin, a p-glycoprotein inhibitor, sensitizes radiation-treated cancer cells by increasing DNA damage and inducing G2 arrest. Journal: Investigational new drugs 20120801 Salinomycin MRL Commodity (previous) ppm Note: The residue definition is Salinomycin only.

Following oral administration, residues are present only at very low concentrations in liver and muscle that fall below the limit of decision of the assay within 2 days in poultry. Very toxic to turkeys.
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2021-04-09T08:41:51Z https://lup.lub.lu.se/student-papers/oai

Mouse LD50 Salinomycin toxicity in turkeys has been reported on numerous occasions. Do not feed to turkeys. 3 Jul 2018 chicken breast, chicken thigh, protein, lysine, methionine, additive and salinomycin sodium in the control feed mixtures of broiler chickens on  15 Dec 2016 The aim of present study was to evaluate the potential synergistic effect of salinomycin and nisin on gastrointestinal tract microbial ecology and  12 Mar 2004 The most commonly used coccidiostats in poultry are the polyether ionophores such as narasin and salinomycin. This paper presents a rapid  economic impact on the poultry industry and is highly prevalent in chicken anticoccidial drugs which were salinomycin, robenidine and decoquinate at  (50:50), with or without added salinomycin (120 mg per animal day-1).


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Cancer and cancer stem cell targeting agents : A focus on

This paper presents a rapid and simple method for the screening of residues of these two coccidiostatic compounds in poultry and eggs.

kaninerna - Swedish-English Dictionary - Glosbe

About 43% of these are veterinary medicine, 6% are other animal drugs, and 3% are pharmaceutical intermediates. A wide variety of salinomycin options are available to you, such as cattle, horse, and aquatic animals. Anticoccidial drugs are extensively used in the poultry industry to control the infection of the single-cell protozoa of the genus Eimeria.

EC legislation on veterinary drug residues will soon be extended to cover poultry. This will require the development of rapid assays to screen for the presence of residual concentrations of this and other drugs in poultry meat. Use Bio-Cox 60 Granular to provide salinomycin sodium concentrations ranging from 40-60 g/ton (0.0044% to 0.0066%) for the prevention of coccidiosis in broiler, roaster and replacement chickens caused by Eimeria tenella, E. Poultry coccidia are generally host-specific, and the different species parasitize specific parts of the intestine. However, in game birds, including quail, the coccidia may parasitize the entire intestinal tract. Coccidia are distributed worldwide in poultry, game birds reared in captivity, and wild birds. (Also see Cryptosporidiosis.) Salinomycin Na+ ionophores are metabolized in the liver by cytochrome P450 enzymes, and are excreted mostly into bile and feces as parent compound and metabolites in poultry.